3 September 2021

Pedro Brandão wins the prize for the best poster in the Organic and Biomolecular Chemistry Section for a poster entitled: “Isatin as a Central “Puzzle Piece” for Multicomponent Reactions (MCRs)”, P20 at the International Symposium on Synthesis and Catalysis (ISySyCat21), 31 August to 3 September 2021.

July 2021

The past two weeks were very eventful with two accepted papers; one in Synthetic Communications (finally, on Pedro Barrulas’s compounds) and the other in ACS Medicinal Chemistry letters (on Pedro Brandão’s work). Congratulations to all involved.

February 2021

It was great to have this highlight article accepted by ChemComm (work from the first lockdown).

Stereoselective Benzilic Acid Rearrangements: New Advances on an Old Story – Chemical Communications (RSC Publishing)

November 5 2020

We are really pleased to have our work on our novel lightweight semi-conductor molecules accepted in ChemComm.!divAbstract

Thanks to everyone involved!!

July 1 2020

Our paper has reached the 100 citation milestone. .

April 29 2020

It was great to file our European patent application for our novel organic semiconductors; Novel Pentacyclic Diamides with Optoelectronic Applications, Methods to Produce them and uses thereof, N/Ref: PPP 2020/19883. This is an invention developed in collaboration with João Paulo Ramalho from the Chemistry Dept. University of Evora and Luís Branco’s team from NOVA-id-FCT. We hope that this will lead to some real-life applications, watch this space…..

Feb 28 2020

Anthony J. Burke has been elected Fellow of ChemPubSoc Europe.

Jan 17 2020

Pedro Brandão from our group was awarded the prize for the best poster in Organic Chemistry by the Portuguese Chemical Society at the 13th National Meeting on Organic Chemistry that took place at the University of Aveiro. The title of the communication  was: Engaging isatins in multicomponent reactions – Ugi adducts with promising biological activity.

Congratulations Pedro.

Dec 21 2019

Both Carolina Marques and Elisabete Carreiro have been selected to give oral presentations at the forthcoming 13the National Meeting on Organic Chemistry in Aveiro in January.

June 21 2019

We welcome three new members to our group; Tereza Hofmanová (an Erasmus visiting student from the University of Hradec Králové, Czech Republic), Marina Costa (Research assistant within out NAQUIBIO project) and Amina Moutayakine (joint PhD student with José Padrón from the Institute of Bioorganic Chamistry at the University of La Laguna, University of Tenerife).

June 7 2019

See Pedro Brandão’s interview for EFMC at:

May 6 2019

A big congratulations to Pedro Brandão – a CatSuS PhD student from our group – who will be attending the European School of Medicinal Chemistry ESMEC, in Saffi (Italy) from 30th June – 4th July ( He will give  a presentation on his PhD work. Well done Pedro.

April 3 2019

Our group was very saddened to hear of the passing of Prof. Peter Carrott (director of the CQE-UE) on the 1st of April. Our condolences go his wife and children.

March 2019

Catarina Amorim attended the 4th MuTaLig Cost Action Training school from the 6-8th March in Hamburg. It was an excellent experience.

24 February 2019

Anthony Burke gave a talk entitled “Isatin-Triazole Hybrids: Lymphoma Anti-Proliferation and BuChE Inbibition” at the 3rd MuTaLig Working Group Meeting at the Faculty of Pharmacy, University of Paris Descartes, Paris.

7 December 2018

Our latest paper on a novel butrylcholinesterase inhibitor that rivals Donepezil and that has been screened in an animal model has been published. See:

10 November 2018

Anthony Burke gave a talk entitled “Synthesizing Chiral Amines the Hydrosilylation Way: Organocatalysis with Cinchona-Amides”, 8th Spanish Portuguese Japanese Organic Chemistry Symposium (8th SPJ-OCS, 9-10 Nov. 2018), Kyoto, Japan.

13 October 2018

Registration for ISySyCat2019 is now open at

15 September

Our book: Active Pharmaceutical Ingredients in Synthesis, Catalytic Processes in Research and Development, is now out!!

15 September

Our multi-disciplinary project “NAQUIBIODPSA: Obtaining Veterinary Medications from Chitosan Hydrogel Immobilized Silver Nanoparticles” Alentejo 2020, Co–Promotion, Ref. ALT20-03-247-FEDER-033578), funded to a value of 757.986 €  will start on 1st Oct 2018.

7 September

Anthony Burke delivered a talk entitled “Asymmetric Ketimine Hydrosilylation using Chinchona-Picolinamide Organocatalysts”, at the 7th EuChem Conference on Nitrogen Ligands, held in the University of Lisbon.

26 July 2018

Anthony Burke delivered a talk entitled “Catalytic Coupling Methods for Accessing Biological Active Targets , in the chemistry department, University of Alicante, Spain.

24 July 2018

Congrats to both Sónia and João for passing their thesis oral exams successfully this afternoon!

19 July 2018

Congrats to Léticia for passing her final year thesis oral exam with flying colours. Hopefully our paper based on some of her work will be accepted soon.

7 July 2018

History of catalysis in Portugal. file:///E:/aDocumentos%20Laptop%20Novo/Papers/Editorials/2017/ChemCatChem/Editorial/Pombeiro_et_al-2018-ChemCatChem%20(3).pdf

3 July 2018

Anthony Burke delivered a talk entitled “Exploring New Catalytic Methods for Accessing New Medicines: Cancer and Alzheimers Disease Therapeutics”  at Ciencia2018 Encontro com a Ciência e a Tecnologia  em Portugal , International Conference Centre, Lisbon.

22 June 2018

Anthony Burke delivered a talk entitled “New developments in the war against Alzheimer’s disease” at the second International Congress of Geriatrics and Mental Health in Mealhada, Portugal.

24 March 2018

Anthony Burke delivered a talk entitled “Fun with Catalysis: Making New Medicines” at the 6th National Meeting of Portuguese Chemistry Students (VI ENEQUI) at the University of Covilhã.

16 March 2018

Anthony Burke gave a talk entitled ” STD-NMR-in silico  Screening: An Effective Combination for Validating ChE and MAO-B Dual Inhibition” at the 2nd COST MuTaLig Working Group meeting in La Laguna, Tenerife. (

27 February 2018

Anthony Burke had 110 citations (ISI) for all published work in 2017.

1 February 2018

Our work on the development of an acetylcholinesterase and butrylcholinesterase inhibitor (which gave good results in a mouse model) was highlighted in this month’s issue of “Ensino Magazine” (Alzheimer’s Disease Inhibitor, Inibidor contra Alzheimer, p8).

31 January 2018

We congratulate Marina Costa for very successfully defending her MSc thesis, entitled “Síntese assimétrica organocatalítica de aminas quirais na fase homogénea e heterogénea”.

30 January 2018

We congratulate Patricia Bacalhau for very successfully defending her PhD thesis, entitled “Mechansim of Action and Promising Treatments for Neurodegenerative diseases”.

18 January 2018

Anthony Burke presented  a talk entitled “Fun with Cyclizations” (Lecture 1) at the 12 National Meeting on Organic Chemistry of the Portuguese Chemical Society,

We hope this is the first lecture in a series of lectures from our group, called “Fun with Cyclizations”.

14 January 2018

The following book (co-authored by Anthony Burke and Carolina Marques) will be published later this year.

December  2017

Anthony Burke’s interview is published in the 2017 final edition of  Boletim da Sociedade Portuguesa de Química .

3 November 2017

We welcome our new final year project students for 2017-18 to the lab: João Moran, Leticia Veira, Andreia Carreira and Sónia Siquenique. We hope you enjoy your stay.

8 September 2017

The ISySyCat2017 conference was a great success with over 250 participants from 40 countries. We will be organizing the 3rd edition of this conference (ISySyCat2019) to take place in Evora, from 3-6 September 2019.

7July 2017

Congratulations to Luís Galvão and Catarina Amorim for defending their final year degree theses (in Biochemistry) with flying colours, and receiving excellent marks.

12 June 2017

Our research has been high-lighted on the front-page of our university web-portal.

1 June 2017

Anthony Burke will give a talk at the CQE-IST as part of the Chemforum lectures, see:

18 April 2017

Prof. Burke will be guest editor along with Prof. László Somsák (Department of Organic Chemistry, University of Debrecen, Hungary) on the special edition of Molecules  entitled – “Advances in Spiro Compounds”, see:

20 March 2017

We welcome Pedro Brandão to the group, Pedro is a student of the CATSUS PhD program, and is working under the supervision of Prof. Burke, Prof. Marta Pineiro (Chemistry dept, University of Coimbra) and Dr. Maxim Kuznetsov from the Centro Química Estrutural, IST, Lisbon.

17 February 2017

We welcome Arona Pires to the group. Arona will work on the analysis of olive oils by NMR spectroscopy. This work is part of the MedOOmics – Mediterranean Extra Virgin Olive Oil Omics: Profiling and Fingerprinting  project that is coordinated by Prof. Maria João Cabrita, from the plant technology department of the University of Évora.

17 December 2016

The International Symposium on Synthesis & Catalysis 2017 (ISySyCat2017), will take place at the University of Évora, from 5-8 September 2017. We are looking forward to seeing you there.


6 December 2016

We welcome Srikanth Mamidala to the lab. Srikanth is an Erasmus Mundus Leader PhD fellow from the chemistry department of the National Institute of Technology Warangal, India, who will be with us for 10 months.

22 November 2016

Prof. Burke gave a talk entitled Catalysis in medicinal chemistry: Improving firepower for Big diseases,  in the Chemistry department, Università degli Studi di Milano, Italy.

15 November 2016

Prof. Burke gave a talk entitled “Developing New Small-Molecule Cholinesterase Inhibitors: Harnessing the Power of 3-Substituted-3-Hydroxyoxindoles”  World Preclinical Congress – Europe.

26 September 2016

We welcome Margherita Pirola (MSc student) from the group of Prof. Maurizio Benaglia in Milan, who will be working with us for a few weeks as part of a joint collaboration on the asymmetric synthesis of novel rivastigmine analogues for cholinesterase inhibition.

13 September 2016

Congratulations to Rita Rodrigues for recently passing her oral exam by defending her final year project thesis entitled “Synthesis of new hybrid cinchona-1,2,3-triazoles and cholinesterase inhibition studies”.

8 September 2016

Congratulations to Cátia Guarda for successfully defending her master’s thesis. She can now relax a bit before taking on her next clallenge.

31 August 2016

Carolina Marques’ work on chiral oxindole-triazole hybrids has been accepted for publication in ChemCatChem. Congratulations to her!

18 July 2016

We welcome Davide Brenna (2nd year PhD student) from the group of Prof. Maurizio Benaglia in Milan, who will be working with us on novel rivastigmine analogues till the end of July.

4 July 2016

Congratulations to Sílvia Fernandes for successfully defending her master’s thesis. She is now off for a short stay in the lab of Prof. Maurizio Benaglia in Milan.

28 June 2016

Congratulations to Bruno Mendes for successfully defending his final year project thesis.

27 June 2016

We welcome Le Nguyen to the group. Le is an Erasmus BSc visiting student who will be with us for some weeks.

20 June 2016

We welcome Xaiza Aniban to the group. Xaiza is an Erasmus visiting masters student who will be with us for 10 months. She will work on chiral dibenzodiazepines.

June 2016

Our paper – New Click-Chemistry Methods for 1,2,3-triazoles: Synthesis: Recent Advances and Applications, J. Totobenazara, A.J. Burke ,  Tetrahedron Letters Digests, 2015 , 56, 2853-59. Available on-line 9 Abril 2015. . This is still the top downloaded paper over 90 days.

May 2016

We are currently doing the ground-work for the International Symosium on Synthesis and Catalysis 2017 (ISySyCat2017) that will take place between 5 and the 8th of September 2017.

April 2016

Both Dr. Carolina Marques and Ms. Silvia Fernandes gave oral presentations at  the

5th Portuguese Young Chemists Meeting (5th PYCheM) – 1st European Young Chemists Meeting (1st EYCheM), Guimarães, Portugal, 26-29 April 2016.

March 2016

On the 4th March, Prof. Burke, gave a seminar at the School of Chemistry, University College Dublin. The talk was entitled: “Adventures and Misadventures with Imines and Analogues– Targeting Biologically Active Compounds ,”.

February  2016

Congratulations to Dr. Hugo Viana for successfully defending his PhD thesis entitled “Studies on the Catalytic Intramolecular Arylation – Application of Continuous Flow Systems”. We wish him the best of luck.

December 2015

Congratulations to Dr. Daniela Peixoto for successfully defending her PhD thesis entitled “Catalytic Intramolecular Arylation of Imines and Analogues:  Potential Drugs for Neurodegenerative Diseases”. We wish her the best of luck.

14 September 2015

Davide Brenna a PhD student from Maurizio Benaglia’s group at the Department of Chemistry – Università degli Studi di Milano, has joined our group for a short stay. He will work on a novel asymmetric route to the Alzheimer’s disease drug, Rivastigmine. This is part of our collaborative project Cooperação Científica e Tecnológica FCT/ITALIA CNR -2015/2016.

4 September 2015

The ISySyCat2015 conference that took place at the University of Evora was an enormous success, with over 150 participants from 27 countries. Planning for ISySyCat2017 is currently underway.

10 March 2015

Prof. Burke will be giving a plenary lecture at the 7th Spanish Portuguese Japanese Organic Chemistry Symposium  (7th SPJ-OCS), June 23-26, 2015 , in Seville, Spain. ( ) His talk title will be announced shortly.

Also, don´t miss the International Symposium on Synthesis and Catalysis  (ISySyCat2015) that will be chaired by Prof. Burke and will take place at the University of Evora from 2-4 September 2015. See:

January 2015

Finally out…

Catalytic Arylation Methods: From the Academic Lab to Industrial Processes, Burke and Markes, Wiley-VCH.

26 September 2014

Congratulations to Silvia Fernandes, João Mendes and Ana Mourato for recently successfully defending their final year project dissertations with flying colours.

4th September 2014


Prof. Anthony Burke and Dr. Carolina Marques are very pleased to announce that production of their book; Catalytic Arylation Methods – From the Academic Lab to Industrial Processes (which is being published by Wiley-VCH) is in full swing, and will be available during the coming months (see:

8th July 2014

Congratulations to Cátia Guarda for recently passing her oral exam with flying colors by successfully defending her final year project thesis on: Synthesis of 4-hydroxy-tetra-hydroisoquinolinones and derivatives and evaluation of their biological activity.